My friend just bought one of these... my first thought was cute, but not practical.... it was backpack style..
I didn't like that the surface is not wipe-off.. and the bottle pockets are INSIDE the mesh zipper area? no quick-grab for any supplies, the bag has to be "disassembled" so to speak to get into anything. Plus, that main compartment will require (IMO) smaller "organizer" bags. The clothes will get all jumbley I think. I'm interested to know what she thinks when she uses it. Oh wait I think there is a zipper section at the top. Just seemed inefficient as far as accessibility of the stuff inside. Now, if you're traveling it's probably great!